Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | ACP1 | P24666 | 4/20 | 0.58 |
| ▸ | PTPRF | P10586 | 2/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.58 |
| ▸ | PTPRB | P23467 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689183 | 1.00 | PPARG (0.70) | PPARGAKR1B1ENPP2NLRP3PTPN1 | |
| SCHEMBL12177171 | 0.96 | PPARG (0.71) | PPARGAKR1B1ENPP2PTPN1ACP1 | |
| SCHEMBL6253587 | 0.92 | PPARG (0.69) | PPARGENPP2PTPN1ACP1PTPRF | |
| SCHEMBL6253581 | 0.92 | PPARG (0.69) | PPARGENPP2PTPN1ACP1PTPRF | |
| SCHEMBL12177758 | 0.91 | PPARG (0.82) | PPARGAKR1B1ENPP2NLRP3PTPN1 | |
| SCHEMBL6686162 | 0.91 | PPARG (0.77) | PPARGENPP2PTPN1ACP1PTPRF | |
| SCHEMBL6686160 | 0.91 | PPARG (0.77) | PPARGENPP2PTPN1ACP1PTPRF | |
| SCHEMBL12177742 | 0.89 | PPARG (0.68) | PPARGAKR1B1ENPP2PTPN1ACP1 | |
| SCHEMBL12177684 | 0.87 | ENPP2 (0.67) | PPARGAKR1B1ENPP2PTPN1ACP1 | |
| SCHEMBL12177142 | 0.87 | PPARG (0.63) | PPARGENPP2PTPN1ACP1PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | disclosed |