Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872991 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL3305087 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL2343127 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL22612526 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL22612511 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL23930717 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL17772493 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL22240 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL7823853 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL8049901 | 0.91 | GPR84 (0.64) | ACE2GPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925792-B1 | Insoluble insulin compositions for controlling blood glucose | LILLY CO ELI (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-1396272-A1 | Insoluble Insulin Compositions for Controlling Blood Glucose | Eli Lilly & Company (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20030144181-A1 | Insoluble compositions for controlling blood glucose | BRADER MARK LAURENCE (US) | 2003-07-31 | — | — | US | disclosed |
| EP-0925792-A2 | Insoluble compositions for controlling blood glucose | ELI LILLY AND COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |