SCHEMBL6689595

SCHEMBL6689595

NC(=O)SCc1ccc(Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 8/20 0.68
L3MBTL1 Q9Y468 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALDH1A1 P00352 3/20 0.51
MAPT P10636 2/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CYP2C19 P33261 2/20 0.50
CYP2C9 P11712 1/20 0.50
NOS1 P29475 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL7059838 0.93 IDO1 (0.59) IDO1L3MBTL1TDP1ALDH1A1MAPT
SCHEMBL23560151 0.81 CA2 (0.54) IDO1L3MBTL1TDP1ALDH1A1CYP2C19
SCHEMBL8345822 0.81 TDP1 (0.62) IDO1L3MBTL1TDP1ALDH1A1GAA
SCHEMBL3321590 0.81 IDO1 (1.00) IDO1NOS1
SCHEMBL15424828 0.80 TDP1 (0.62) IDO1L3MBTL1TDP1ALDH1A1GAA
SCHEMBL29271495 0.79 IDO1 (0.68) IDO1ALDH1A1MAPTNOS1MEN1
Hydrochloric Acid SCHEMBL3815185 0.79 IDO1 (1.00) IDO1NOS1
SCHEMBL14611678 0.79 IDO1 (0.57) IDO1L3MBTL1TDP1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL11842725 0.79 TDP1 (0.61) IDO1L3MBTL1TDP1ALDH1A1GAA
SCHEMBL27984966 0.79 IDO1 (0.68) IDO1L3MBTL1TDP1ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5928997-A APPLYING ON MONOCOTYLEDON AND DICOTYLEDON WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1999-07-27 US claimed
CN-104640447-A Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxphenyl) pyridine-2-carboxylic acid or a derivative thereof and vlcfa synthesis and fatty acid/lipid synthesis inhibiting herbicides DOW AGROSCIENCES LLC 2015-05-20 CN disclosed
WO-2004080938-A1 SYNTHESIS OF S-ALKYL AND S-ARYL THIOCARBAMATES, ONE-POT TWO-STEP GENERAL SYNTHESIS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2004-09-23 WO disclosed
US-6686494-B1 PRECURSOR THIOL REAGENT IS FIRST REACTED WITH TRICHLOROACETYL CHLORIDE TO PRODUCE S-ALKYL OR S-ARYL TRICHLOROACETYL THIOESTER INTERMEDIATE, WHICH IS REACTED WITH AN AMINE TO YIELD THIOCARBAMATE PRODUCT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2004-02-03 US disclosed
US-5928997-A APPLYING ON MONOCOTYLEDON AND DICOTYLEDON WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1999-07-27 US disclosed
CN-85101429-B Microcapsules and process for making microcapsules 斯多佛化学有限公司 1988-08-17 CN disclosed
CN-85101429-A The process of microencapsulation and preparing microcapsules 1987-01-17 CN disclosed