Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 9/20 | 0.82 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | FABP3 | P05413 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689432 | 0.99 | FABP4 (0.80) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6688856 | 0.90 | FABP4 (1.00) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6691562 | 0.89 | FABP4 (0.79) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6684662 | 0.88 | FABP4 (0.78) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6688676 | 0.87 | FABP4 (0.77) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6683805 | 0.86 | FABP4 (0.65) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6686673 | 0.86 | FABP4 (0.65) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6689537 | 0.84 | FABP4 (0.71) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6684199 | 0.83 | FABP4 (0.73) | FABP4HDAC6HDAC1HDAC10FABP3 | |
| SCHEMBL6685705 | 0.82 | FABP4 (0.72) | FABP4HDAC6HDAC1HDAC10FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| US-20140363522-A1 | Compositions and Methods for Treating and/or Preventing Cancer by Inhibiting Fatty Acid Binding Proteins | NIH - DEITR | 2014-12-11 | — | — | US | disclosed |
| US-8748470-B2 | Methods for treating ovarian cancer by inhibiting fatty acid binding proteins | THE UNIVERSITY OF CHICAGO (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120289570-A1 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING CANCER BY INHIBITING FATTY ACID BINDING PROTEINS | NIH | 2012-11-15 | — | — | US | disclosed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |