Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.69 |
| ▸ | TUBB | P07437 | 1/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.69 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.69 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.69 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.69 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.67 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.67 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689907 | 1.00 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5472587 | 0.84 | MDM2 (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5472583 | 0.84 | MDM2 (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12484385 | 0.82 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12484381 | 0.82 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ic261 SCHEMBL3697594 | 0.80 | CSNK1D (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ic261 SCHEMBL29467414 | 0.80 | CSNK1D (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ic261 SCHEMBL2786157 | 0.80 | CSNK1D (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ic261 SCHEMBL905701 | 0.80 | CSNK1D (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6689531 | 0.79 | ESRRA (0.53) | MDM2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |