Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5791758 | 0.97 | DPP4 (0.65) | DPP4LMNAPOLBMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719022 | 0.91 | DPP4 (0.62) | DPP4LMNAPOLBMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719313 | 0.90 | DPP4 (0.60) | DPP4LMNAPOLBMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719165 | 0.89 | LMNA (0.57) | DPP4LMNAPOLBMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719079 | 0.88 | DPP4 (0.74) | DPP4LMNAMAPK1ALDH1A1CHRM1 | |
| Trifluoroacetic Acid SCHEMBL6688447 | 0.88 | DPP4 (0.71) | DPP4LMNAMAPK1ALDH1A1CHRM1 | |
| Trifluoroacetic Acid SCHEMBL5719052 | 0.88 | DPP4 (0.71) | DPP4LMNAMAPK1ALDH1A1CHRM1 | |
| Trifluoroacetic Acid SCHEMBL5719028 | 0.88 | DPP4 (0.71) | DPP4LMNAMAPK1ALDH1A1CHRM1 | |
| Trifluoroacetic Acid SCHEMBL5719118 | 0.88 | DPP4 (0.60) | DPP4LMNAPOLBMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5718870 | 0.87 | DPP4 (0.69) | DPP4LMNAMAPK1ALDH1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | DPP4 1/4885LMNA 4075/4885POLB 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.