Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.65 |
| ▸ | FAP | Q12884 | 5/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6383569 | 0.92 | DPP4 (0.65) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL6689943 | 0.89 | DPP4 (0.61) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL6380855 | 0.89 | DPP4 (0.73) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| Acetic Acid Methyl Ester SCHEMBL6691055 | 0.88 | DPP4 (0.62) | DPP4FAPDPP9 | |
| Acetonitrile SCHEMBL6380038 | 0.88 | DPP4 (0.65) | DPP4FAPDPP9 | |
| Ethyl Acetate SCHEMBL5718858 | 0.86 | DPP4 (0.60) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL5718973 | 0.86 | DPP4 (0.74) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL5718963 | 0.84 | DPP4 (0.67) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6383383 | 0.84 | DPP4 (0.61) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| Acetic Acid Methyl Ester SCHEMBL5718823 | 0.84 | DPP4 (0.50) | DPP4FAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | DPP4 1/4885FAP 402/4885DPP9 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.