Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.73 |
| ▸ | FAP | Q12884 | 5/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6383569 | 0.94 | DPP4 (0.65) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL6382540 | 0.92 | DPP4 (0.73) | DPP4FAPDPP9 | |
| Acetic Acid SCHEMBL6689937 | 0.89 | DPP4 (0.65) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL5275960 | 0.85 | DPP4 (1.00) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL6689943 | 0.84 | DPP4 (0.61) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6380586 | 0.84 | DPP4 (0.64) | DPP4FAPDPP9 | |
| SCHEMBL5719403 | 0.83 | DPP4 (0.77) | DPP4FAPDPP9L3MBTL1ALDH1A1 | |
| SCHEMBL6380848 | 0.83 | DPP4 (0.58) | DPP4FAPDPP9ALDH1A1 | |
| SCHEMBL5719225 | 0.83 | DPP4 (0.73) | DPP4FAPDPP9L3MBTL1 | |
| SCHEMBL5719250 | 0.83 | DPP4 (0.83) | DPP4FAPDPP9L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | claimed |
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | disclosed |