Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367855 | 0.95 | MEN1 (0.63) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL7364771 | 0.94 | MEN1 (0.62) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL7367538 | 0.94 | MEN1 (0.62) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL20553331 | 0.86 | MEN1 (0.67) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL21775649 | 0.86 | MEN1 (0.67) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL21775559 | 0.86 | MEN1 (0.67) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL7327969 | 0.84 | MEN1 (0.68) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL7364366 | 0.84 | MEN1 (0.63) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL7367871 | 0.84 | MEN1 (0.63) | MEN1OPRM1OPRD1KMT2ALMNA | |
| SCHEMBL11606524 | 0.84 | MEN1 (0.71) | MEN1OPRM1OPRD1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096217-A1 | USE OF N-TYPE CALCIUM CHANNEL INHIBITORS IN TREATING DEMYELINATING DISEASES | EISAI LONDON RESEARCH LABORATORIES LIMITED (GB) | 2004-11-11 | — | — | WO | claimed |
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |