Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 15/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300097 | 0.85 | NOTUM (0.76) | NOTUMCYP2D6CYP2C9DRD2DRD4 | |
| SCHEMBL3895361 | 0.84 | NOTUM (1.00) | NOTUMDRD2DRD4UCHL1 | |
| SCHEMBL30730960 | 0.84 | NOTUM (1.00) | NOTUMDRD2DRD4UCHL1 | |
| SCHEMBL13390815 | 0.78 | NOTUM (0.68) | NOTUMDRD2DRD4POLBUCHL1 | |
| SCHEMBL13390819 | 0.78 | NOTUM (0.68) | NOTUMCYP2D6CYP2C9DRD2DRD4 | |
| SCHEMBL3300094 | 0.78 | NOTUM (0.68) | NOTUMDRD2DRD4POLBUCHL1 | |
| SCHEMBL6688366 | 0.76 | NOTUM (0.55) | NOTUM | |
| SCHEMBL6687673 | 0.75 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL3300297 | 0.75 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL4532424 | 0.75 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLBUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085394-A1 | 7-NITROINDOLINE DERIVATIVES AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2004-10-07 | — | — | WO | disclosed |