Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.54 |
| ▸ | CTSK | P43235 | 10/20 | 0.54 |
| ▸ | CTSL | P07711 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693232 | 0.92 | CTSS (0.56) | CTSSCTSKCTSL | |
| SCHEMBL6685373 | 0.88 | CTSS (0.51) | CTSSCTSKCTSL | |
| SCHEMBL6690182 | 0.88 | CTSS (0.53) | CTSSCTSKCTSL | |
| SCHEMBL6687326 | 0.87 | CTSS (0.50) | CTSSCTSKCTSL | |
| SCHEMBL6689155 | 0.87 | CTSS (0.50) | CTSSCTSKCTSL | |
| SCHEMBL6685237 | 0.86 | CTSS (0.51) | CTSSCTSKCTSL | |
| SCHEMBL6689372 | 0.86 | CTSS (0.55) | CTSSCTSKCTSL | |
| SCHEMBL6693346 | 0.85 | CTSS (0.69) | CTSSCTSKCTSL | |
| SCHEMBL6690425 | 0.85 | CTSS (0.53) | CTSSCTSKCTSL | |
| SCHEMBL6690040 | 0.84 | CTSS (0.57) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |