Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 10/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.74 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.74 |
| ▸ | CYP2E1 | P05181 | 4/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493639 | 0.88 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL5014459 | 0.86 | CYP2A6 (0.68) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL3604362 | 0.85 | CYP2A6 (1.00) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL13300562 | 0.84 | CYP2A6 (0.74) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL6724033 | 0.83 | CYP2A6 (0.68) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL5017551 | 0.81 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL1132959 | 0.81 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL5015514 | 0.81 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL5017549 | 0.81 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL8204568 | 0.81 | CYP2A6 (0.80) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220120-A1 | Novel anhydrolide derivatives having antibacterial activity | VO NHA HUU (US) | 2004-11-04 | — | — | US | claimed |
| WO-2004069854-A1 | NOVEL ANHYDROLIDE DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | ENANTA PHARMACEUTICALS. INC. (US) | 2004-08-19 | — | — | WO | claimed |
| US-6720308-B1 | Anhydrolide derivatives having antibacterial activity | ENANTA PHARMACEUTICALS, INC. | 2004-04-13 | — | — | US | claimed |
| CN-1234718-C | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-01-04 | — | — | CN | disclosed |
| US-20040220120-A1 | Novel anhydrolide derivatives having antibacterial activity | VO NHA HUU (US) | 2004-11-04 | — | — | US | disclosed |
| WO-2004069854-A1 | NOVEL ANHYDROLIDE DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | ENANTA PHARMACEUTICALS. INC. (US) | 2004-08-19 | — | — | WO | disclosed |
| US-6720308-B1 | Anhydrolide derivatives having antibacterial activity | ENANTA PHARMACEUTICALS, INC. | 2004-04-13 | — | — | US | disclosed |
| CN-1464880-A | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2003-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220120-A1 | Novel anhydrolide derivatives having antibacterial activity | GALE, GNE, GMDS | CYP2A6 1059/4885CYP2C19 2319/4885CYP3A4 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.