Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929781 | 0.80 | MCHR1 (0.66) | MCHR1KMT2AMEN1MAPTPOLB | |
| SCHEMBL19603062 | 0.80 | MCHR1 (0.67) | MCHR1PDE10AMIFNQO2KMT2A | |
| SCHEMBL873587 | 0.78 | MCHR1 (0.65) | MCHR1PDE10AKMT2AMEN1ALDH1A1 | |
| SCHEMBL873240 | 0.78 | MCHR1 (0.70) | MCHR1PDE10ANQO2PDE3BPDE3A | |
| SCHEMBL15648746 | 0.78 | MCHR1 (0.65) | MCHR1PDE10ANQO2KMT2AMEN1 | |
| SCHEMBL27823137 | 0.78 | MCHR1 (0.46) | MCHR1KMT2AMEN1 | |
| SCHEMBL30886901 | 0.77 | MCHR1 (0.62) | MCHR1PDE10AMIFNQO2KMT2A | |
| SCHEMBL1655715 | 0.77 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL16106785 | 0.77 | MCHR1 (0.62) | MCHR1PDE10AMIFNQO2KMT2A | |
| SCHEMBL28260922 | 0.77 | MCHR1 (0.62) | MCHR1PDE10AMIFNQO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452224-A | Multifunctional quinoline derivatives as anti-neurodegenerative agents | ANNJI PHARM CO LTD | 2016-03-30 | — | — | CN | claimed |
| CN-110072857-A | 1, 3-disubstituted cyclobutanone or azetidine derivatives as hematopoietic prostaglandin D synthase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-107001316-A | It is used as the Carbostyril derivative of antiseptic | 诺华股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-103492377-B | As the triazolopyridine compounds of PIM kinase inhibitor | ARRAY BIOPHARMA INC. (US) | 2016-04-20 | — | — | CN | disclosed |
| CN-105452224-A | Multifunctional quinoline derivatives as anti-neurodegenerative agents | ANNJI PHARM CO LTD | 2016-03-30 | — | — | CN | disclosed |
| CN-103492377-A | Triazolopyridine compounds as PIM kinase inhibitors | ARRAY BIOPHARMA INC | 2014-01-01 | — | — | CN | disclosed |
| WO-2004080371-A2 | INJECTABLE ISOTONIC SOLUTION OF GATIFLOXACIN PRE-DILUTED IN GLUCOSE. | HALEX ISTAR INDÚSTRIA FARMACÊUTICA LTDA. (BR) | 2004-09-23 | — | — | WO | disclosed |