SCHEMBL6690430 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.45

▸	KMT2A	Q03164	1/20	0.45

▸	POLB	P06746	1/20	0.45

▸	CTSS	P25774	5/20	0.44

▸	KDM4A	O75164	1/20	0.43

▸	EPHX1	P07099	1/20	0.43

▸	CTSL	P07711	1/20	0.40

▸	KCNQ2	O43526	2/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	CCR3	P51677	1/20	0.40

▸	CRHBP	P24387	2/20	0.39

▸	CRHR2	Q13324	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6689715	0.90	CTSS (0.52)	CTSSCTSL
SCHEMBL6694225	0.88	EPHX1 (0.45)	MEN1KMT2ACTSSEPHX1CTSL
SCHEMBL6687363	0.88	EPHX1 (0.45)	MEN1KMT2ACTSSEPHX1CTSL
SCHEMBL6685626	0.87	CTSS (0.47)	MEN1KMT2ACTSSCTSL
SCHEMBL6692653	0.83	CTSS (0.43)	CTSSEPHX1CTSLCCR3
SCHEMBL6694181	0.82	CTSS (0.51)	CTSSCTSL
SCHEMBL5844425	0.80	CTSS (0.58)	CTSSCTSL
SCHEMBL5844420	0.80	CTSS (0.58)	CTSSCTSL
SCHEMBL6691194	0.80	CTSS (0.41)	CTSSEPHX1CTSLCCR3
SCHEMBL6688775	0.80	CTSS (0.41)	CTSSEPHX1CTSLCCR3CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004084842-A2	INHIBITORS OF CATHEPSIN S	IRM LLC (BM)	2004-10-07	—	—	WO	disclosed