Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714953 | 1.00 | TSHR (0.52) | TSHRGABRA1GABRB2PPARGCSNK1E | |
| SCHEMBL22444754 | 0.98 | TSHR (0.50) | TSHRGABRA1GABRB2PPARGCSNK1E | |
| SCHEMBL22444751 | 0.98 | TSHR (0.50) | TSHRGABRA1GABRB2PPARGCSNK1E | |
| SCHEMBL4146572 | 0.98 | TSHR (0.50) | TSHRGABRA1GABRB2PPARGCSNK1E | |
| SCHEMBL8517638 | 0.98 | TSHR (0.50) | TSHRGABRA1GABRB2PPARGCSNK1E | |
| SCHEMBL4981071 | 0.94 | TSHR (0.53) | TSHRGABRA1GABRB2PPARGCSNK1E | |
| SCHEMBL4738271 | 0.88 | TSHR (0.55) | TSHRGABRA1GABRB2PPARGALDH1A1 | |
| SCHEMBL8772490 | 0.85 | TSHR (0.48) | TSHRGABRA1GABRB2PPARGCSNK1E | |
| SCHEMBL982569 | 0.85 | TSHR (0.52) | TSHRGABRA1GABRB2CSNK1EMEN1 | |
| SCHEMBL8828951 | 0.85 | TSHR (0.52) | TSHRGABRA1GABRB2CSNK1EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447309-A | Multi-carbon bridged phenol compound prepared from phenol and polyalcohol compound and synthesis method | 薪业资源(江苏)科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0110405-B1 | ANTIINFLAMMATORY/ANTIALLERGIC COMPOUNDS | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4794188-A | LIPOXYGENASE INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| US-4778931-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| US-4567184-A | Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies | USV PHARMACEUTICAL CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0110405-A2 | Antiinflammatory/antiallergic compounds | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1984-06-13 | — | — | EP | disclosed |
| US-4025553-A | Production of o-hydroxybenzyl alcohols | SHIONOGI & CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |