Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50816 | 0.87 | APP (0.65) | APPMAPTTDP1L3MBTL1CA12 | |
| SCHEMBL1343630 | 0.84 | CA12 (0.65) | APPMAPTTDP1L3MBTL1CA12 | |
| SCHEMBL8067325 | 0.83 | APP (0.56) | APPMAPTTDP1L3MBTL1CA12 | |
| SCHEMBL11610878 | 0.81 | DRD4 (0.49) | L3MBTL1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL1323797 | 0.81 | APP (0.54) | APPMAPTL3MBTL1CA12CA1 | |
| SCHEMBL17879939 | 0.81 | APP (0.59) | APPMAPTCA12CA1CA2 | |
| SCHEMBL2414300 | 0.80 | MAPT (0.56) | APPMAPTTDP1L3MBTL1CA12 | |
| SCHEMBL5824848 | 0.80 | CA12 (0.52) | APPMAPTTDP1L3MBTL1CA12 | |
| SCHEMBL7029327 | 0.80 | CA1 (0.58) | APPMAPTTDP1L3MBTL1CA12 | |
| SCHEMBL13042289 | 0.79 | APP (0.57) | APPMAPTL3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825348-B2 | Antiviral compounds | ACADEMIA SINICA (TW) | 2004-11-30 | — | — | US | disclosed |
| US-20040002475-A1 | Dna genome | ACADEMIA SINICA (TW) | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002475-A1 | Dna genome | DNA2, OGG1, UNG | APP 3812/4885MAPT 4872/4885TDP1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.