Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 11/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689254 | 0.83 | SCN9A (0.53) | — | |
| SCHEMBL6689256 | 0.83 | SCN9A (0.53) | — | |
| SCHEMBL6686767 | 0.82 | CD274 (0.53) | PDCD1CD274SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6686469 | 0.79 | KMT2A (0.53) | SMN1; SMN2KMT2AMEN1GAARAB9A | |
| SCHEMBL6686470 | 0.79 | KMT2A (0.53) | SMN1; SMN2KMT2AMEN1GAARAB9A | |
| SCHEMBL6688731 | 0.78 | CD274 (0.45) | PDCD1CD274SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6688726 | 0.78 | CD274 (0.45) | PDCD1CD274SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6254681 | 0.78 | PDCD1 (0.41) | PDCD1CD274SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6254676 | 0.78 | PDCD1 (0.41) | PDCD1CD274SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6694008 | 0.78 | PDCD1 (0.44) | PDCD1CD274RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |