SCHEMBL669080

SCHEMBL669080

C#Cc1cccc(N=Nc2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
CYP1A1 P04798 1/20 0.42
CYP1B1 Q16678 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
NPC1 O15118 1/20 0.41
TRPA1 O75762 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CRHR1 P34998 3/20 0.40
PTPN1 P18031 1/20 0.40
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669079 1.00 ALDH1A1 (0.52) ALDH1A1CYP1A1CYP1B1MEN1KMT2A
SCHEMBL9861852 0.82 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL9861869 0.82 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL17517613 0.80 CYP1A1 (0.43) CYP1A1CYP1B1MEN1KMT2ARAB9A
SCHEMBL29406199 0.78 TSHR (0.54) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL12561923 0.78 CYP1A1 (0.42) CYP1A1CYP1B1MEN1KMT2ARAB9A
SCHEMBL14288982 0.78 CA12 (0.46) CYP1A1CYP1B1MEN1KMT2ARAB9A
SCHEMBL14323609 0.78 ALDH1A1 (0.75) ALDH1A1CYP1A1CYP1B1MEN1KMT2A
SCHEMBL14323608 0.78 ALDH1A1 (0.75) ALDH1A1CYP1A1CYP1B1MEN1KMT2A
SCHEMBL7911018 0.77 CA1 (0.41) ALDH1A1CYP1A1CYP1B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012024029-A1 CONTROLLING CONCENTRATIONS OF ANIONS WITH LIGHT USING ARYL-TRIAZOLE FOLDAMERS INDIANA RESEARCH & TECHNOLOGY CORPORATION (US) 2012-02-23 WO disclosed