Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.61 |
| ▸ | CTSL | P07711 | 11/20 | 0.61 |
| ▸ | CTSK | P43235 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692456 | 0.88 | CTSS (0.62) | CTSSCTSLCTSK | |
| SCHEMBL6687678 | 0.87 | CTSS (0.71) | CTSSCTSLCTSK | |
| SCHEMBL6690860 | 0.87 | CTSS (0.61) | CTSSCTSLCTSKABL1BCR | |
| SCHEMBL6685947 | 0.86 | CTSS (0.61) | CTSSCTSLCTSK | |
| SCHEMBL6685236 | 0.86 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL6690368 | 0.86 | CTSS (0.58) | CTSSCTSLCTSKMEN1KMT2A | |
| SCHEMBL6690040 | 0.84 | CTSS (0.57) | CTSSCTSLCTSKABL1BCR | |
| SCHEMBL6687985 | 0.83 | CTSS (0.56) | CTSSCTSLCTSK | |
| SCHEMBL6693346 | 0.83 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL6689691 | 0.83 | CTSS (0.56) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |