Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.90 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.82 |
| ▸ | PDE2A | O00408 | 3/20 | 0.82 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.73 |
| ▸ | PTGFR | P43088 | 1/20 | 0.73 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.73 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.73 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777289 | 0.95 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5800203 | 0.95 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5836363 | 0.87 | TBXA2R (1.00) | TBXA2RPTGDRPDE2APTGDR2 | |
| SCHEMBL13317737 | 0.87 | TBXA2R (0.90) | TBXA2RPTGDRPDE2APTGER1PTGFR | |
| SCHEMBL4548360 | 0.87 | TBXA2R (0.90) | TBXA2RPTGDRPDE2APTGER1PTGFR | |
| SCHEMBL5775019 | 0.87 | TBXA2R (0.85) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5777761 | 0.87 | TBXA2R (0.89) | TBXA2RPTGDRPDE2APTGER1PTGFR | |
| SCHEMBL10312500 | 0.85 | TBXA2R (0.90) | TBXA2RPTGDRPDE2APTGDR2 | |
| SCHEMBL13416145 | 0.85 | TBXA2R (0.90) | TBXA2RPTGDRPDE2APTGDR2 | |
| SCHEMBL14472808 | 0.85 | TBXA2R (0.71) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-A2 | DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-A]INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Merck Frosst Canada & Co. (CA) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094830-A2 | DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-a]-INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA & CO. (CA) | 2002-11-28 | — | — | WO | disclosed |