Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.85 |
| ▸ | PDE2A | O00408 | 3/20 | 0.82 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800203 | 0.92 | TBXA2R (1.00) | TBXA2RPDE2APTGDR | |
| SCHEMBL5777289 | 0.92 | TBXA2R (1.00) | TBXA2RPDE2APTGDR | |
| SCHEMBL5774002 | 0.91 | TBXA2R (1.00) | TBXA2RPDE2APTGDR | |
| SCHEMBL5797320 | 0.91 | TBXA2R (1.00) | TBXA2RPDE2APTGDR | |
| SCHEMBL6690976 | 0.87 | TBXA2R (0.90) | TBXA2RPDE2APTGDR | |
| SCHEMBL5812466 | 0.86 | TBXA2R (0.82) | TBXA2RPDE2APTGDR | |
| SCHEMBL5836363 | 0.84 | TBXA2R (1.00) | TBXA2RPDE2APTGDR | |
| SCHEMBL5774518 | 0.81 | TBXA2R (0.81) | TBXA2RPDE2APTGDR | |
| SCHEMBL5835872 | 0.81 | TBXA2R (0.84) | TBXA2RPDE2APTGDR | |
| SCHEMBL5776492 | 0.80 | TBXA2R (0.79) | TBXA2RPDE2APTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |