Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.76 |
| ▸ | USP2 | O75604 | 3/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687323 | 0.85 | MAPT (0.81) | MAPTHSD17B10MAPK1USP2NPSR1 | |
| SCHEMBL21682206 | 0.84 | ALDH1A1 (0.70) | MAPTHSD17B10MAPK1USP2NPSR1 | |
| SCHEMBL21753695 | 0.84 | LRRK2 (1.00) | MAPTHSD17B10RAB9ANPC1TSHR | |
| SCHEMBL26606572 | 0.81 | MAPT (0.72) | MAPTHSD17B10MAPK1USP2NPSR1 | |
| SCHEMBL6684638 | 0.79 | MAPT (0.84) | MAPTHSD17B10MAPK1USP2LMNA | |
| SCHEMBL26606566 | 0.79 | MAPT (0.68) | MAPTHSD17B10MAPK1USP2NPSR1 | |
| SCHEMBL1094219 | 0.78 | MAPT (0.77) | MAPTMAPK1USP2LMNARAB9A | |
| SCHEMBL17073220 | 0.78 | MAPT (0.98) | MAPTHSD17B10MAPK1USP2NPSR1 | |
| SCHEMBL665069 | 0.77 | MAPT (0.81) | MAPTLMNARAB9ANPC1TP53 | |
| SCHEMBL21772281 | 0.77 | RXFP1 (0.75) | MAPTHSD17B10MAPK1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078115-A2 | BENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF ROTAVIRUS INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA, INCORPORATED (US) | 2004-09-16 | — | — | WO | claimed |