Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.79 |
| ▸ | RAB9A | P51151 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1880565 | 0.89 | ALDH1A1 (1.00) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL29359913 | 0.89 | ALDH1A1 (1.00) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL29372602 | 0.89 | ALDH1A1 (1.00) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL30120715 | 0.81 | KDM4E (0.83) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL21112920 | 0.81 | MAPT (0.83) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL26983883 | 0.81 | KDM4E (0.83) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL31037131 | 0.80 | ALDH1A1 (0.82) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL4481328 | 0.80 | ALDH1A1 (0.82) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL30612325 | 0.80 | ALDH1A1 (0.82) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL8964851 | 0.76 | ALDH1A1 (0.75) | NPC1RAB9AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004104051-A1 | BIMOLECULAR PHOTOINITIATOR SYSTEMS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-12-02 | — | — | WO | disclosed |