Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 7/20 | 0.58 |
| ▸ | LCK | P06239 | 2/20 | 0.58 |
| ▸ | RET | P07949 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689322 | 0.92 | PIK3CD (0.69) | KDRFLT1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL28646400 | 0.86 | KDR (0.80) | KDRFLT1HDAC3HDAC4HDAC1 | |
| SCHEMBL6684007 | 0.86 | EGFR (0.74) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14964688 | 0.85 | EGFR (0.80) | KDRFLT1HDAC3HDAC4HDAC1 | |
| SCHEMBL28635157 | 0.85 | EGFR (0.79) | KDRFLT1EGFRLCKRET | |
| SCHEMBL6689825 | 0.84 | KDR (0.64) | KDRFLT1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL6692082 | 0.84 | SRC (0.79) | KDRHDAC1EGFRLCKRET | |
| SCHEMBL6691540 | 0.84 | KDR (0.66) | KDRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6689903 | 0.83 | KDR (0.63) | KDRFLT1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL28637305 | 0.83 | ABCG2 (0.82) | KDRFLT1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |