Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490500 | 0.86 | LDHA (0.67) | LDHAALDH1A1TACR1KMT2AMEN1 | |
| SCHEMBL4725563 | 0.82 | TAAR1 (0.60) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL6688761 | 0.81 | LDHA (0.76) | LDHAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL490334 | 0.80 | MAPK1 (0.51) | LDHAALDH1A1TACR1KMT2APOLB | |
| SCHEMBL21689950 | 0.78 | SLC7A5 (0.55) | LDHAALDH1A1KMT2AMEN1 | |
| SCHEMBL20721733 | 0.78 | LDHA (0.51) | LDHAKMT2AMEN1POLB | |
| SCHEMBL31644253 | 0.77 | LDHA (0.42) | LDHATACR1KMT2AMEN1 | |
| SCHEMBL11466889 | 0.77 | LDHA (0.69) | LDHAKMT2AMEN1POLB | |
| SCHEMBL5680559 | 0.76 | LDHA (0.49) | LDHATACR1KMT2AMEN1 | |
| SCHEMBL27922388 | 0.75 | ACACB (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |