Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.61 |
| ▸ | ACACB | O00763 | 1/20 | 0.59 |
| ▸ | ACACA | Q13085 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14809777 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL14810000 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL6691762 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL14809190 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL2457383 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL2337342 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL15463466 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL14809101 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL4993301 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA | |
| SCHEMBL810904 | 1.00 | ACLY (0.61) | ACLYACACBACACATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171688-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | BAR-TANA JACOB (IL) | 2004-09-02 | — | — | US | disclosed |
| US-20020037876-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RESEARCH DEVELOPMENT COMPANY OF HEBREW UNIVERSITY OF JERUSALEM | 2002-03-28 | — | — | US | disclosed |
| US-6303653-B1 | THERAPY OF HEPATOCYTE NUCLEAR FACTOR-4.ALPHA..SUP.1 (HNF-4) MEDIATED DISEASE BY ADMINISTERING CARBOXYLIC ACID OR ITS DERIVATIVE WHICH INHIBITS HNF-4 CONTROLLED TRANSCRIPTION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-10-16 | — | — | US | disclosed |