Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506387 | 0.82 | MME (0.58) | MMEACENPSR1NAALAD2ALDH1A1 | |
| SCHEMBL3506385 | 0.82 | MME (0.58) | MMEACENPSR1NAALAD2ALDH1A1 | |
| SCHEMBL7379335 | 0.81 | MME (0.70) | MMEACENPSR1NAALAD2MMP2 | |
| SCHEMBL9068541 | 0.81 | MME (0.70) | MMEACENPSR1NAALAD2MMP2 | |
| SCHEMBL6770152 | 0.79 | MME (0.55) | MMEACENPSR1NAALAD2ALDH1A1 | |
| SCHEMBL3090103 | 0.78 | MME (0.48) | MMEACENPSR1L3MBTL1 | |
| SCHEMBL3090098 | 0.78 | MME (0.48) | MMEACENPSR1L3MBTL1 | |
| SCHEMBL8385283 | 0.77 | MME (0.53) | MMEACENPSR1NAALAD2MMP2 | |
| SCHEMBL17633984 | 0.77 | MME (0.53) | MMEACENPSR1NAALAD2MMP2 | |
| SCHEMBL8697148 | 0.76 | MME (0.52) | MMENPSR1NAALAD2L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071505-A2 | RADIOLABELLED D-AMINO ACIDS FOR USE IN DIAGNOSIS WITH SPECT AND PET AND SYSTEMIC RADIONUCLIDE THERAPY | MALLINCKRODT INC. (US) | 2004-08-26 | — | — | WO | disclosed |