Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678977 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6688952 | 0.95 | ALDH1A1 (0.59) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6678048 | 0.92 | ALDH1A1 (0.62) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6678024 | 0.92 | MAPT (0.58) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6687984 | 0.92 | MAPT (0.58) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6689380 | 0.90 | MAPT (0.58) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6684428 | 0.90 | MAPT (0.58) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6689606 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6692630 | 0.89 | PTGS1 (0.56) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL6684359 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |