Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322139 | 0.85 | GAA (0.42) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL6324231 | 0.84 | GAA (0.42) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6317179 | 0.83 | KMT2A (0.42) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6322647 | 0.82 | GAA (0.43) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6316797 | 0.80 | KMT2A (0.38) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6317151 | 0.80 | KMT2A (0.36) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6315271 | 0.79 | KMT2A (0.41) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6323695 | 0.79 | KMT2A (0.41) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6316297 | 0.79 | MAPK14 (0.40) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL6317350 | 0.79 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377549-A1 | FUNCTIONALIZED HETEROCYCLES AS MODULATORS OF CHEMOKINE RECEPTOR FUNCTION AND METHODS OF USE THEREFOR | Millennium Pharmaceuticals, Inc. (US) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002072549-A1 | FUNCTIONALIZED HETEROCYCLES AS MODULATORS OF CHEMOKINE RECEPTOR FUNCTION AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-09-19 | — | — | WO | disclosed |