Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 9/20 | 0.53 |
| ▸ | UGCG | Q16739 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692501 | 1.00 | GHSR (0.53) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6692499 | 1.00 | GHSR (0.53) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6691369 | 0.94 | GHSR (0.52) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6695245 | 0.94 | GHSR (0.52) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6691512 | 0.89 | GHSR (0.42) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6691993 | 0.89 | GHSR (0.53) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6691393 | 0.89 | GHSR (0.53) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6691397 | 0.89 | GHSR (0.53) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6691541 | 0.89 | GHSR (0.54) | GHSRUGCGCYP3A4CCKBRP2RX7 | |
| SCHEMBL6691543 | 0.89 | GHSR (0.54) | GHSRUGCGCYP3A4CCKBRP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002802-B1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER PROD INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6194578-B1 | GROWTH HORMONE SECRETAGOGUES; USEFUL FOR PROPHYLAXIS AND THERAPY OF OSTEOPOROSIS AND/OR FRAILTY, INSULIN RESISTANCE IN MAMMALS, CONGESTIVE HEART FAILURE, OBESITY, ACCELERATING BONE FRACTURE REPAIR REDUCING CACHEXIA AND PROTEIN LOSS | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-1002802-A1 | Dipeptide derivatives as growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-05-24 | — | — | EP | disclosed |