Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.68 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692202 | 1.00 | PPARG (0.68) | PPARGAKR1B1MAOAMAOBENPP2 | |
| SCHEMBL6686162 | 0.89 | PPARG (0.77) | PPARGENPP2LMNAMEN1KMT2A | |
| SCHEMBL6686160 | 0.89 | PPARG (0.77) | PPARGENPP2LMNAMEN1KMT2A | |
| SCHEMBL15816888 | 0.86 | PPARG (0.60) | PPARGAKR1B1MAOAMAOBENPP2 | |
| SCHEMBL15816886 | 0.86 | PPARG (0.60) | PPARGAKR1B1MAOAMAOBENPP2 | |
| SCHEMBL15816884 | 0.86 | PPARG (0.60) | PPARGAKR1B1MAOAMAOBENPP2 | |
| SCHEMBL6686570 | 0.84 | PPARG (0.86) | PPARGENPP2MAPTMEN1ALDH1A1 | |
| SCHEMBL6692673 | 0.84 | PPARG (0.86) | PPARGENPP2MAPTMEN1ALDH1A1 | |
| SCHEMBL5468379 | 0.83 | MEN1 (0.67) | AKR1B1ENPP2MAPTMEN1ALDH1A1 | |
| SCHEMBL5468375 | 0.83 | MEN1 (0.67) | AKR1B1ENPP2MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | disclosed |