SCHEMBL6692299

SCHEMBL6692299

CCO/N=C(C(\CC)=N\N=C\c1ccccc1N(C)C(=O)OC)/c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPK14 Q16539 2/20 0.37
LIPE Q05469 5/20 0.35
CYP1A1 P04798 2/20 0.32
CYP1B1 Q16678 2/20 0.32
MAOB P27338 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
LSS P48449 1/20 0.31
TLR7 Q9NYK1 1/20 0.30
LMNA P02545 1/20 0.30
LTA4H P09960 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6692302 1.00 MEN1 (0.37) MEN1KMT2AMAPK14LIPECYP1A1
SCHEMBL6696020 0.93 MAPK14 (0.38) MEN1KMT2AMAPK14LIPEKDM4E
SCHEMBL6696019 0.93 MAPK14 (0.38) MEN1KMT2AMAPK14LIPEKDM4E
SCHEMBL6691769 0.91 MAPK14 (0.36) MEN1KMT2AMAPK14LIPECYP1A1
SCHEMBL6691767 0.91 MAPK14 (0.36) MEN1KMT2AMAPK14LIPECYP1A1
SCHEMBL6695270 0.91 MEN1 (0.38) MEN1KMT2AMAPK14LIPECYP1A1
SCHEMBL6695269 0.91 MEN1 (0.38) MEN1KMT2AMAPK14LIPECYP1A1
SCHEMBL6691051 0.88 MAPK14 (0.34) MEN1KMT2AMAPK14LIPE
SCHEMBL6697305 0.88 MAPK14 (0.34) MEN1KMT2AMAPK14LIPE
SCHEMBL6693770 0.82 MAPK14 (0.37) MEN1KMT2AMAPK14LIPECYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US claimed
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect CBR3, CBR1, CYP1B1 MEN1 3045/4885KMT2A 3292/4885MAPK14 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.