SCHEMBL6696020

SCHEMBL6696020

CCON=C(C(CC)=NN=Cc1ccccc1N(C)C(=O)OC)c1ccc(Oc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.38
GCGR P47871 1/20 0.38
TLR7 Q9NYK1 2/20 0.34
TLR8 Q9NR97 1/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 2/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN11 Q06124 1/20 0.33
RAF1 P04049 1/20 0.33
CHEK2 O96017 1/20 0.33
PTGER4 P35408 1/20 0.32
PPARG P37231 1/20 0.32
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LIPE Q05469 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6696019 1.00 MAPK14 (0.38) MAPK14GCGRTLR7TLR8MAPT
SCHEMBL6692299 0.93 MEN1 (0.37) MAPK14TLR7MAPTKDM4EKMT2A
SCHEMBL6692302 0.93 MEN1 (0.37) MAPK14TLR7MAPTKDM4EKMT2A
SCHEMBL6691769 0.85 MAPK14 (0.36) MAPK14TLR7MAPTKDM4EKMT2A
SCHEMBL6691767 0.85 MAPK14 (0.36) MAPK14TLR7MAPTKDM4EKMT2A
SCHEMBL6695270 0.85 MEN1 (0.38) MAPK14TLR7MAPTKDM4EKMT2A
SCHEMBL6695269 0.85 MEN1 (0.38) MAPK14TLR7MAPTKDM4EKMT2A
SCHEMBL6691003 0.84 GCGR (0.40) MAPK14GCGRTLR7TLR8MAPT
SCHEMBL6691007 0.84 GCGR (0.40) MAPK14GCGRTLR7TLR8MAPT
SCHEMBL6697305 0.82 MAPK14 (0.34) MAPK14KMT2AMEN1LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US claimed
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect CBR3, CBR1, CYP1B1 MAPK14 2557/4885GCGR 2261/4885TLR7 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.