Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692337 | 1.00 | NR4A2 (0.48) | NR4A2NR4A1NR4A3MAOBSRD5A2 | |
| SCHEMBL5361204 | 0.74 | MEN1 (0.54) | NR4A2NR4A1NR4A3SMN1; SMN2MEN1 | |
| SCHEMBL5361197 | 0.74 | MEN1 (0.54) | NR4A2NR4A1NR4A3SMN1; SMN2MEN1 | |
| SCHEMBL29958502 | 0.71 | NR4A2 (0.56) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL6130315 | 0.70 | KMT2A (0.41) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5702967 | 0.69 | KMT2A (0.66) | MAOBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5368099 | 0.69 | MAPT (0.66) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5368105 | 0.69 | MAPT (0.66) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL228477 | 0.69 | NR4A2 (1.00) | NR4A2NR4A1NR4A3MAOBSRD5A2 | |
| SCHEMBL4059143 | 0.69 | NR4A2 (1.00) | NR4A2NR4A1NR4A3MAOBSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058990-A1 | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORPORATION | 2004-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058990-A1 | Thrombopoietin mimetics | MPL, THPO, TEK | NR4A2 3092/4885NR4A1 3466/4885NR4A3 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.