SCHEMBL228477

SCHEMBL228477

O=C(O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 6/20 1.00
NR4A1 P22736 1/20 1.00
NR4A3 Q92570 1/20 1.00
SRD5A2 P31213 2/20 0.90
PLA2G4B P0C869 1/20 0.84
MAOB P27338 1/20 0.74
PARP10 Q53GL7 1/20 0.74
RXRA P19793 5/20 0.72
RXRB P28702 5/20 0.72
NPC1 O15118 1/20 0.72
POLB P06746 1/20 0.72
RAB9A P51151 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
MEN1 O00255 1/20 0.71
KMT2A Q03164 1/20 0.71
RXRG P48443 1/20 0.69
PKM P14618 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4059143 1.00 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL6830467 1.00 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL11603952 0.98 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL11603274 0.98 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
Hydrochloric Acid SCHEMBL8544438 0.98 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL11273693 0.98 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL4949143 0.95 NR4A2 (0.90) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL1221359 0.95 NR4A2 (0.90) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
Benzil SCHEMBL7771752 0.93 NR4A2 (0.87) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
Hydrochloric Acid SCHEMBL8378883 0.93 NR4A2 (0.87) NR4A2NR4A1NR4A3SRD5A2PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115302920-A Antibacterial, mildewproof and antiviral leather and preparation method thereof 天守(福建)超纤科技股份有限公司 2022-11-08 CN claimed
CN-115212314-A Albumin-bound antitumor drug and nano-composite thereof, and preparation method and application thereof 沈阳药科大学 2022-10-21 CN claimed
EP-2993055-B1 Web-shaped heat-sensitive recording material with a protective layer MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2019-04-03 EP claimed
EP-3352991-B1 HEAT SENSITIVE RECORDING MATERIAL MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2019-01-30 EP claimed
EP-2279732-A2 Compounds and compositions for delivering active agents Emisphere Technologies, Inc. (US) 2011-02-02 EP claimed
CN-101914118-A Trehalose derivant and preparation method and application thereof UNIV SHANDONG 2010-12-15 CN claimed
JP-2007537301-A 2007-12-20 JP claimed
CN-1964939-A Compounds and compositions for delivering active agents EMISPHERE TECH INC (US) 2007-05-16 CN claimed
EP-1756039-A4 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECH INC (US) 2007-05-02 EP claimed
EP-1756039-A2 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS Emisphere Technologies, Inc. (US) 2007-02-28 EP claimed
US-20030149110-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases HU LAIN-YEN (US) 2003-08-07 US claimed
WO-2003045902-A1 BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES WARNER-LAMBERT COMPANY LLC (US) 2003-06-05 WO claimed
EP-1314723-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases WARNER-LAMBERT COMPANY (US) 2003-05-28 EP claimed
CN-1132508-A Piperazine derivatives REORDATI IND CHIMICA E FARMACE (CH) 1996-10-02 CN claimed
EP-0301587-B1 LIQUID CRYSTAL COMPOUNDS AND INTERMEDIATES THEREOF WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-15 EP claimed
EP-0301587-A1 Liquid crystal compounds and intermediates thereof WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1989-02-01 EP claimed
US-4719198-A CONTAINING P-BENZYLOXYBENZOIC ACID BENZYL ESTER; OIL-STABLE IMAGES JUJO PAPER CO., LTD. (JP) 1988-01-12 US claimed
EP-0066813-B1 HEAT-SENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1985-08-21 EP claimed
EP-0059975-B1 THERMORESPONSIVE RECORDING SHEET Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-06-26 EP claimed
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149110-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases BCAT1, BCAT2, ABAT NR4A2 4337/4885NR4A1 4778/4885NR4A3 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.