SCHEMBL6692458

SCHEMBL6692458

C=C(C)C(=O)OCCOC(=O)C(CCCC)OP(=O)(O)O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
THRB P10828 1/20 0.45
SMPD1 P17405 3/20 0.41
FDPS P14324 1/20 0.35
PTPN1 P18031 1/20 0.34
LPAR3 Q9UBY5 3/20 0.33
LPAR1 Q92633 2/20 0.33
LPAR2 Q9HBW0 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858838 0.82 TSHR (0.53) TSHRTHRBSMPD1FDPSPTPN1
Phosphoric Acid SCHEMBL139116 0.80 TSHR (0.51) TSHRTHRBFDPSALDH1A1CA1
SCHEMBL28746443 0.79 SMPD1 (0.57) TSHRSMPD1FDPSPTPN1LPAR3
SCHEMBL5173693 0.79 TSHR (0.54) TSHRTHRBSMPD1FDPSPTPN1
SCHEMBL15752949 0.78 TSHR (0.45) TSHRTHRBSMPD1FDPSPTPN1
SCHEMBL5173564 0.78 TSHR (0.56) TSHRTHRBSMPD1FDPSPTPN1
SCHEMBL5174125 0.78 TSHR (0.56) TSHRTHRBSMPD1FDPSPTPN1
SCHEMBL5172999 0.78 TSHR (0.56) TSHRTHRBSMPD1FDPSPTPN1
Hexane SCHEMBL1436393 0.77 TSHR (0.64) TSHRTHRBLPAR3LPAR1LPAR2
Phosphoric Acid SCHEMBL28347911 0.77 TSHR (0.58) TSHRTHRBSMPD1FDPSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462079-A1 Dental composition GC Corporation (JP) 2004-09-29 EP disclosed