Phosphoric Acid

Phosphoric Acid

SCHEMBL139116

C=C(C)C(=O)OCCOC(=O)C(CC)CCCC.C=C(C)C(=O)OCCOC(=O)C(CC)CCCC.O=P(O)(O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.51
CA2 P00918 6/20 0.49
CA1 P00915 4/20 0.49
THRB P10828 1/20 0.45
MAPK1 P28482 1/20 0.41
FDPS P14324 1/20 0.35
GAA P10253 1/20 0.34
XBP1 P17861 1/20 0.34
ATM Q13315 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95647 0.85 TSHR (0.44) TSHRCA2CA1THRBALDH1A1
SCHEMBL6331921 0.85 TSHR (0.44) TSHRCA2CA1THRBALDH1A1
Ethylene SCHEMBL11863511 0.81 CA2 (0.66) TSHRCA2CA1MAPK1GAA
Ethylene SCHEMBL3377191 0.81 CA2 (0.66) TSHRCA2CA1MAPK1GAA
Ethylene SCHEMBL8349417 0.81 CA2 (0.66) TSHRCA2CA1MAPK1GAA
Ethylene SCHEMBL8349438 0.81 CA2 (0.66) TSHRCA2CA1MAPK1GAA
Ethylene SCHEMBL8346683 0.81 CA2 (0.66) TSHRCA2CA1MAPK1GAA
SCHEMBL154056 0.81 CA2 (0.70) TSHRCA2CA1MAPK1GAA
SCHEMBL6692458 0.80 TSHR (0.51) TSHRCA2CA1THRBFDPS
SCHEMBL27238501 0.80 THRB (0.45) TSHRCA2CA1THRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230026650-A1 DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION DENTSPLY SIRONA INC. (US) 2023-01-26 US claimed
EP-4072503-A1 DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION Dentsply Sirona Inc. (US) 2022-10-19 EP claimed
WO-2021116275-A1 DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION DENTSPLY SIRONA INC. (US) 2021-06-17 WO claimed
EP-3834805-A1 DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION DENTSPLY SIRONA Inc. (US) 2021-06-16 EP claimed
US-9326917-B2 Dental masking compound VOCO GMBH (DE) 2016-05-03 US claimed
US-9079994-B2 Polymerizable compositions GC CORPORATION (JP) 2015-07-14 US claimed
US-20140138864-A1 KIT AND METHOD FOR INDIRECT CHAIRSIDE PRODUCTION OF COMPOSITE INLAYS VOCO GMBH (DE) 2014-05-22 US claimed
US-20120093741-A1 DENTAL MASKING COMPOUND VOCO GMBH (DE) 2012-04-19 US claimed
US-6916858-B2 Dental adhesive composition GC CORPORATION (JP) 2005-07-12 US claimed
EP-3342393-B1 DENTAL CEMENT G C DENTAL IND CORP (JP) 2023-11-29 EP disclosed
WO-2023188631-A1 GLASS COMPOSITION 株式会社ジーシー 2023-10-05 WO disclosed
WO-2023190678-A1 ADHESIVE COMPOSITION FOR DENTAL USE 株式会社ジーシー 2023-10-05 WO disclosed
WO-2023053787-A1 METHOD FOR PRODUCING DENTAL FILLER, DENTAL FILLER, AND DENTAL COMPOSITION 株式会社ジーシー 2023-04-06 WO disclosed
WO-2023054284-A1 DENTAL ADHESIVE COMPOSITION 株式会社ジーシー 2023-04-06 WO disclosed
US-7968617-B2 Filler containing composition and process for production and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-06-28 US disclosed
US-20100240797-A1 POLYMERIZABLE COMPOSITION GC CORPORATION (JP) 2010-09-23 US disclosed
US-20100204421-A1 INITIATORS IN TWO COMPONENTS, AND POLYMERIZABLE COMPOSITION USING THE SAME GC CORPORATION (JP) 2010-08-12 US disclosed
US-20090247665-A1 FILLER CONTAINING COMPOSITION AND PROCESS FOR PRODUCTION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2009-10-01 US disclosed
US-20090018234-A1 DENTAL CEMENT GC CORPORATION (JP) 2009-01-15 US disclosed
US-6916858-B2 Dental adhesive composition GC CORPORATION (JP) 2005-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026650-A1 DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION KIT, PIP5K1C, GRIK1 TSHR 4603/4885CA2 421/4885CA1 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.