Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20871505 | 0.98 | SPHK1 (0.56) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL28869095 | 0.98 | SPHK1 (0.56) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL20492541 | 0.92 | OPRM1 (0.46) | OPRM1SPHK1TP53CYP3A4TRPV1 | |
| SCHEMBL16649198 | 0.90 | OPRM1 (0.62) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL24392963 | 0.87 | OPRM1 (0.59) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL21217006 | 0.87 | SPHK1 (0.60) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL19441327 | 0.87 | SPHK1 (0.60) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL2338645 | 0.87 | SPHK1 (0.60) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL2332779 | 0.87 | SPHK1 (0.60) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL12728004 | 0.87 | SPHK1 (0.60) | OPRM1SPHK1TP53LAP3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832092-B1 | ORALLY ACTIVE ADENOSINE KINASE INHIBITORS | METABASIS THERAPEUTICS INC (US) | 2004-11-17 | — | — | EP | disclosed |
| EP-0832092-A1 | ORALLY ACTIVE ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040706-A1 | ORALLY ACTIVE ADENOSINE KINASE INHIBITORS | GENSIA-SICOR (US) | 1996-12-19 | — | — | WO | disclosed |