Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721766 | 1.00 | CYP1A2 (0.36) | CYP1A2ALDH1A1ACHECHRM5ADRA2C | |
| SCHEMBL6691821 | 0.97 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL6692444 | 0.92 | — | — | |
| SCHEMBL27995317 | 0.89 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL6691843 | 0.87 | — | — | |
| SCHEMBL825364 | 0.83 | CYP1A2 (0.34) | CYP1A2ALDH1A1ACHECHRM5ADRA2C | |
| SCHEMBL6697762 | 0.83 | CYP1A2 (0.34) | CYP1A2ALDH1A1ACHECHRM5ADRA2C | |
| SCHEMBL28494132 | 0.82 | CYP1A2 (0.36) | CYP1A2ALDH1A1SIGMAR1 | |
| SCHEMBL7643953 | 0.80 | CYP1A2 (0.36) | CYP1A2ALDH1A1ACHECHRM5ADRA2C | |
| SCHEMBL30189746 | 0.80 | CYP1A2 (0.36) | CYP1A2ALDH1A1ACHECHRM5ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004523599-A | — | — | 2004-08-05 | — | — | JP | claimed |
| EP-1353961-A2 | (CYCLOALKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2003-10-22 | — | — | EP | claimed |
| US-6469112-B2 | SOLID TITANIUM CATALYST COMPONENT; AN ORGANOALUMINUM COMPOUND; AND AN ORGANOSILICON COMPOUND COMPRISING AT LEAST ONE (CYCLOALKYL)METHYL GROUP; MAKING HIGH XYLENE SOLUBLE POLYOLEFINS WITH CATALYTIC EFFICIENCY | ENGELHARD CORPORATION | 2002-10-22 | — | — | US | claimed |
| US-20020028893-A1 | (Cycloalkyl) methyl silanes as external donors for polyolefin catalysts | W. R. GRACE & CO.-CONN. | 2002-03-07 | — | — | US | claimed |
| WO-2002016444-A2 | (CYCLOAKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2002-02-28 | — | — | WO | claimed |
| EP-1353961-A2 | (CYCLOALKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2003-10-22 | — | — | EP | disclosed |
| US-6469112-B2 | SOLID TITANIUM CATALYST COMPONENT; AN ORGANOALUMINUM COMPOUND; AND AN ORGANOSILICON COMPOUND COMPRISING AT LEAST ONE (CYCLOALKYL)METHYL GROUP; MAKING HIGH XYLENE SOLUBLE POLYOLEFINS WITH CATALYTIC EFFICIENCY | ENGELHARD CORPORATION | 2002-10-22 | — | — | US | disclosed |
| US-20020028893-A1 | (Cycloalkyl) methyl silanes as external donors for polyolefin catalysts | W. R. GRACE & CO.-CONN. | 2002-03-07 | — | — | US | disclosed |
| WO-2002016444-A2 | (CYCLOAKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2002-02-28 | — | — | WO | disclosed |