SCHEMBL825364

SCHEMBL825364

CO[Si](C)(CC1CCCCC1)OC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
ALDH1A1 P00352 1/20 0.31
ACHE P22303 1/20 0.30
CHRM5 P08912 2/20 0.30
ADRA2C P18825 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6697762 1.00 CYP1A2 (0.34) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL6692863 0.98 CYP1A2 (0.31) CYP1A2
SCHEMBL6690577 0.93
SCHEMBL6690880 0.87
SCHEMBL721766 0.83 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL6692807 0.83 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL17750053 0.81 CYP1A2 (0.34) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL6691821 0.80 CYP1A2 (0.32) CYP1A2
SCHEMBL7643953 0.78 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL7445835 0.78 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004523599-A 2004-08-05 JP claimed
EP-1353961-A2 (CYCLOALKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS ENGELHARD CORPORATION (US) 2003-10-22 EP claimed
US-6469112-B2 SOLID TITANIUM CATALYST COMPONENT; AN ORGANOALUMINUM COMPOUND; AND AN ORGANOSILICON COMPOUND COMPRISING AT LEAST ONE (CYCLOALKYL)METHYL GROUP; MAKING HIGH XYLENE SOLUBLE POLYOLEFINS WITH CATALYTIC EFFICIENCY ENGELHARD CORPORATION 2002-10-22 US claimed
US-20020028893-A1 (Cycloalkyl) methyl silanes as external donors for polyolefin catalysts W. R. GRACE & CO.-CONN. 2002-03-07 US claimed
WO-2002016444-A2 (CYCLOAKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS ENGELHARD CORPORATION (US) 2002-02-28 WO claimed
US-12559632-B2 Weather-resistant, fungal-resistant, and stain-resistant coatings and methods of applying on wood, masonry, or other porous materials UNIVERSITY OF HOUSTON SYSTEM (US) 2026-02-24 US disclosed
US-12312534-B2 Treating fluid comprising hydrocarbons, water, and polymer CHEVRON U.S.A. INC. (US) 2025-05-27 US disclosed
US-20240067865-A1 TREATING FLUID COMPRISING HYDROCARBONS, WATER, AND POLYMER CHEVRON U.S.A. INC. 2024-02-29 US disclosed
US-11834606-B2 Treating fluid comprising hydrocarbons, water, and polymer CHEVRON U.S.A. INC. (US) 2023-12-05 US disclosed
US-20230323193-A1 PH CONTROL IN FLUID TREATMENT CHEVRON U.S.A. INC. 2023-10-12 US disclosed
CN-116023549-A Prepolymerized catalyst, preparation method and application thereof 中国石油化工股份有限公司 2023-04-28 CN disclosed
US-11591893-B2 PH control in fluid treatment CHEVRON U.S.A. INC. (US) 2023-02-28 US disclosed
EP-1353961-A2 (CYCLOALKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS ENGELHARD CORPORATION (US) 2003-10-22 EP disclosed
US-6469112-B2 SOLID TITANIUM CATALYST COMPONENT; AN ORGANOALUMINUM COMPOUND; AND AN ORGANOSILICON COMPOUND COMPRISING AT LEAST ONE (CYCLOALKYL)METHYL GROUP; MAKING HIGH XYLENE SOLUBLE POLYOLEFINS WITH CATALYTIC EFFICIENCY ENGELHARD CORPORATION 2002-10-22 US disclosed
US-20020028893-A1 (Cycloalkyl) methyl silanes as external donors for polyolefin catalysts W. R. GRACE & CO.-CONN. 2002-03-07 US disclosed
WO-2002016444-A2 (CYCLOAKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS ENGELHARD CORPORATION (US) 2002-02-28 WO disclosed
US-6191232-B1 A PROPYLENE BLOCK COPOLYMER PRODUCED BY CONTINUOUS POLYMERIZATION COMPRISING POLYMER PARTICLES, HAVING RUBBER COMPONENT OF AN ALPHA-OLEFIN HAVING 2 TO 18 CARBON ATOMS; EXCELLENT IN RIGIDITY AND IMPACT RESISTANCE MITSUBISHI CHEMICAL CORPORATION (JP) 2001-02-20 US disclosed
US-5859143-A BLOCK COPOLYMERIZATION REACTION IN PRESENCE OF HYDROGEN AND STEREOSPECIFIC CATALYST CONTAINING COMPOUNDS OF MAGNESIUM, TITANIUM, HALOGEN, ORGANOALUMINUM AND ELECTRON DONOR MITSUBISHI CHEMICAL CORPORATION (JP) 1999-01-12 US disclosed
CN-1027643-C Catalyst component and catalyst for olefin polymerization HIMONT INC (US) 1995-02-15 CN disclosed
CN-1053241-A The catalyst component of olefinic polymerization and catalyzer HIMONT INC (US) 1991-07-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559632-B2 Weather-resistant, fungal-resistant, and stain-resistant coatings and methods of applying on wood, masonry, or other porous materials GMDS, MGAM, STS CYP1A2 1610/4885ALDH1A1 4200/4885ACHE 3969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.