Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.45 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | HTR2A | P28223 | 7/20 | 0.45 |
| ▸ | PRCP | P42785 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637285 | 0.87 | HTR2C (0.50) | HTR2CHTR2BHTR2APRCPKMT2A | |
| SCHEMBL3872517 | 0.80 | TRPV1 (0.49) | HTR2CHTR2BHTR2AMEN1CYP3A4 | |
| SCHEMBL11638324 | 0.80 | PRCP (0.40) | HTR2CHTR2BHTR2APRCPMEN1 | |
| Hydrochloric Acid SCHEMBL3874607 | 0.79 | TRPV1 (0.48) | HTR2CHTR2BHTR2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3883795 | 0.79 | TRPV1 (0.48) | HTR2CHTR2BHTR2AMEN1CYP3A4 | |
| SCHEMBL10668338 | 0.75 | TAAR1 (0.52) | HTR2CHTR2BHTR2APRCPTAAR1 | |
| SCHEMBL11642135 | 0.74 | PRCP (0.50) | HTR2CHTR2BHTR2APRCPCYP2D6 | |
| Hydrochloric Acid SCHEMBL3875713 | 0.72 | TRPV1 (0.35) | HTR2CHTR2BHTR2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3882718 | 0.72 | TRPV1 (0.35) | HTR2CHTR2BHTR2A | |
| SCHEMBL11641902 | 0.70 | PRCP (0.49) | PRCPGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004256527-A | PDE4 INHIBITOR | TANABE SEIYAKU CO LTD | 2004-09-16 | — | — | JP | disclosed |