Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641902 | 0.84 | PRCP (0.49) | PRCPGRIN2BOPRM1OPRK1SIGMAR1 | |
| SCHEMBL11641898 | 0.84 | PRCP (0.49) | PRCPGRIN2BOPRM1OPRK1SIGMAR1 | |
| SCHEMBL11636826 | 0.82 | PRCP (0.41) | PRCP | |
| SCHEMBL11637285 | 0.79 | HTR2C (0.50) | PRCPGRIN2BHTR2AHTR2COPRM1 | |
| SCHEMBL11637332 | 0.77 | ALDH1A1 (0.50) | CHRM2CHRM3TSHR | |
| SCHEMBL6692817 | 0.74 | HTR2C (0.45) | PRCPGRIN2BHTR2AHTR2CHTR2B | |
| SCHEMBL29832657 | 0.74 | PRCP (0.50) | PRCPCHRM3KCNH2 | |
| SCHEMBL11638324 | 0.71 | PRCP (0.40) | PRCPGRIN2BHTR2AHTR2CHTR2B | |
| SCHEMBL9945826 | 0.70 | SIGMAR1 (0.53) | GRIN2BSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL10671567 | 0.70 | HTR2A (0.49) | PRCPSLC6A2SLC6A4SLC6A3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120965-A | SLEEP-PROMOTING AGENTS, ANTI-AGGRESSIVE AGENTS | SANDOZ LTD. (CH) | 1978-10-17 | — | — | US | disclosed |