Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641138 | 0.80 | KMT2A (0.42) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL5510643 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL5177934 | 0.78 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL6694934 | 0.77 | MEN1 (0.59) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL2640937 | 0.77 | HTT (0.41) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL8392178 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL5510183 | 0.76 | TP53 (0.41) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL25336401 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL5512049 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL7748109 | 0.75 | KMT2A (0.39) | MEN1KMT2AALDH1A1GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |