Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 14/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.46 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865561 | 0.70 | AADAT (0.47) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL5894080 | 0.70 | AADAT (0.56) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL10814256 | 0.68 | AADAT (0.50) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL4067713 | 0.66 | AADAT (0.45) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL4067683 | 0.66 | AADAT (0.45) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL2132616 | 0.65 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL3773423 | 0.65 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL31656272 | 0.65 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL2955903 | 0.65 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL4072394 | 0.64 | AADAT (0.43) | AADATKYAT1KYAT3GOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483270-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN PHOSPHORYLASE | Astrazeneca AB (SE) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074532-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN PHOSPHORYLASE | ASTRAZENECA AB (SE) | 2003-09-12 | — | — | WO | disclosed |