⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24658751 | 1.00 | — | — | |
| SCHEMBL20803548 | 0.80 | USP2 (0.35) | — | |
| SCHEMBL19954110 | 0.80 | USP2 (0.35) | — | |
| SCHEMBL9676069 | 0.80 | LMNA (0.44) | — | |
| SCHEMBL28263440 | 0.77 | USP2 (0.41) | — | |
| SCHEMBL11215063 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL28809612 | 0.77 | LMNA (0.33) | — | |
| Trimethylammonium SCHEMBL28390389 | 0.76 | USP2 (0.48) | — | |
| SCHEMBL24658749 | 0.76 | HIF1A (0.46) | — | |
| Trimethylammonium SCHEMBL27954285 | 0.76 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
| US-8956646-B2 | Zwitterionic lipids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-17 | — | — | US | disclosed |
| US-20130216607-A1 | ZWITTERIONIC LIPIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2012024233-A2 | ZWITTERIONIC LIPIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-23 | — | — | WO | disclosed |
| CN-101330943-A | Surface active calcium phosphates | DAVID KANNAR (AU) | 2008-12-24 | — | — | CN | disclosed |
| EP-0109255-A2 | Glycerol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-05-23 | — | — | EP | disclosed |