Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342590 | 0.91 | MAPK1 (0.50) | TP53GAAMAPK1L3MBTL1PKM | |
| SCHEMBL1344045 | 0.89 | MAPK1 (0.49) | TP53GAAMAPK1L3MBTL1PKM | |
| SCHEMBL6704336 | 0.88 | L3MBTL1 (0.46) | TP53GAAMAPK1L3MBTL1PKM | |
| SCHEMBL6700224 | 0.87 | MAPK1 (0.48) | TP53GAAMAPK1L3MBTL1PKM | |
| SCHEMBL1344133 | 0.85 | MAPK1 (0.48) | TP53GAAMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL1343111 | 0.85 | L3MBTL1 (0.45) | TP53GAAMAPK1L3MBTL1PKM | |
| SCHEMBL1343238 | 0.84 | L3MBTL1 (0.51) | TP53GAAMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL1341272 | 0.81 | L3MBTL1 (0.51) | GAAMAPK1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1341969 | 0.81 | L3MBTL1 (0.51) | TP53GAAMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL1343194 | 0.80 | TP53 (0.52) | TP53GAAPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | VTV THERAPEUTICS LLC | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | GCK, GCKR, PDK2 | TP53 2961/4885GAA 48/4885MAPK1 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.