Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | KDM4B | O94953 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683220 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL2642436 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL8880291 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| Bromide SCHEMBL9297985 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL13995798 | 0.78 | GSK3B (0.44) | ALDH1A1GSK3BKDM4E | |
| SCHEMBL28329584 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL27704272 | 0.78 | — | — | |
| SCHEMBL27662308 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL4687160 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL11260646 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242863-A1 | Preparation of cefalosporins intermediates and conversion of said intermediates into active compound precursors | MIAT S.P.A. (IT) | 2004-12-02 | — | — | US | claimed |
| JP-58222076-A | — | — | None | — | — | JP | disclosed |
| JP-59204179-A | — | — | None | — | — | JP | disclosed |
| US-20040242863-A1 | Preparation of cefalosporins intermediates and conversion of said intermediates into active compound precursors | MIAT S.P.A. (IT) | 2004-12-02 | — | — | US | disclosed |
| US-4563534-A | Process for producing 2-(2-aminothiazol-4-yl)glyoxylic acid derivative or a salt thereof, and intermediates therefor and process for producing the intermediates | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| JP-S59204179-A | PREPARATION OF (2-AMINOTHIAZOL-4-YL)GLYOXYLIC ACID DERIVATIVE OR ITS SALT | TOYAMA CHEM CO LTD | 1984-11-19 | — | — | JP | disclosed |
| JP-S58222076-A | 2-AMINOTHIAZOLE DERIVATIVE | TOYAMA CHEM CO LTD | 1983-12-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242863-A1 | Preparation of cefalosporins intermediates and conversion of said intermediates into active compound precursors | PCMT1, CYP2S1, DAO | ALDH1A1 1991/4885MEN1 2745/4885NPC1 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.