Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.87 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.78 |
| ▸ | ACP1 | P24666 | 4/20 | 0.78 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.78 |
| ▸ | PTPRF | P10586 | 2/20 | 0.78 |
| ▸ | PTPRB | P23467 | 2/20 | 0.78 |
| ▸ | PPARG | P37231 | 1/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694151 | 1.00 | ENPP2 (0.87) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL14564276 | 0.93 | ENPP2 (1.00) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL6253581 | 0.86 | PPARG (0.69) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL6253587 | 0.86 | PPARG (0.69) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL1555942 | 0.86 | ENPP2 (0.92) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL1555948 | 0.86 | ENPP2 (0.92) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL15816574 | 0.85 | ENPP2 (0.80) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL15816573 | 0.85 | ENPP2 (0.80) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL15816571 | 0.85 | ENPP2 (0.80) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL12177171 | 0.85 | PPARG (0.71) | ENPP2PTPN1ACP1PTPN2PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | disclosed |