Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 12/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 11/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.54 |
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437841 | 0.90 | P2RY2 (0.59) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL31381447 | 0.89 | P2RY14 (0.56) | P2RY6P2RY2P2RY4POLA1P2RY14 | |
| SCHEMBL8439076 | 0.88 | P2RY2 (0.55) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL8440653 | 0.87 | P2RY2 (0.54) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL8436032 | 0.87 | P2RY2 (0.54) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL8440331 | 0.86 | P2RY2 (0.53) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL8437049 | 0.86 | P2RY2 (0.53) | P2RY6P2RY2P2RY4POLA1P2RY14 | |
| SCHEMBL2011098 | 0.85 | P2RY2 (0.62) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL1457065 | 0.84 | P2RY2 (0.54) | P2RY6P2RY2P2RY4POLA1P2RY14 | |
| SCHEMBL30423444 | 0.83 | P2RY2 (0.60) | P2RY6P2RY2P2RY4POLA1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004512810-A | — | — | 2004-04-30 | — | — | JP | claimed |
| EP-1212416-A2 | NUCLEIC ACID BASED MODULATORS OF GENE EXPRESSION | RIBOZYME PHARMACEUTICALS, INC. (US) | 2002-06-12 | — | — | EP | claimed |
| JP-2001525667-A | — | — | 2001-12-11 | — | — | JP | claimed |
| WO-2001016312-A2 | NUCLEIC ACID BASED MODULATORS OF GENE EXPRESSION | RIBOZYME PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | claimed |
| EP-0980424-A2 | ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-02-23 | — | — | EP | claimed |
| WO-1998050530-A2 | ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE | RIBOZYME PHARMACEUTICALS, INC. (US) | 1998-11-12 | — | — | WO | claimed |
| WO-1998050530-A9 | ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE | RIBOZYME PHARM INC (US) | 1999-03-25 | — | — | WO | disclosed |