SCHEMBL1457065

SCHEMBL1457065

NC=CC[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 12/20 0.54
P2RY4 P51582 8/20 0.54
P2RY6 Q15077 11/20 0.51
POLA1 P09884 1/20 0.50
P2RY14 Q15391 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanide SCHEMBL29185226 0.97 P2RY2 (0.51) P2RY2P2RY4P2RY6POLA1P2RY14
SCHEMBL8437049 0.90 P2RY2 (0.53) P2RY2P2RY4P2RY6POLA1P2RY14
SCHEMBL8440653 0.89 P2RY2 (0.54) P2RY2P2RY4P2RY6POLA1
SCHEMBL31381447 0.87 P2RY14 (0.56) P2RY2P2RY4P2RY6POLA1P2RY14
SCHEMBL8437841 0.87 P2RY2 (0.59) P2RY2P2RY4P2RY6POLA1
SCHEMBL8439076 0.85 P2RY2 (0.55) P2RY2P2RY4P2RY6POLA1
SCHEMBL6694199 0.84 P2RY6 (0.54) P2RY2P2RY4P2RY6POLA1P2RY14
SCHEMBL95680 0.84 P2RY6 (0.54) P2RY2P2RY4P2RY6POLA1
SCHEMBL3635669 0.84 POLG (0.46) P2RY2P2RY4P2RY6POLA1
SCHEMBL5144406 0.84 P2RY2 (0.55) P2RY2P2RY4P2RY6POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636304-B2 2026-05-26 US disclosed
US-20240384261-A1 METHODS, COMPOSITIONS, AND KITS FOR PREPARING SEQUENCING LIBRARY GENEFIRST LIMITED (GB) 2024-11-21 US disclosed
US-20240350621-A1 DOUBLE STRANDED MRNA VACCINES UNIV IOWA RES FOUND (US) 2024-10-24 US disclosed
CN-117795096-A Methods, compositions and kits for preparing sequencing libraries 吉复生物科技有限公司 2024-03-29 CN disclosed
WO-2023014974-A1 DOUBLE STRANDED MRNA VACCINES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2023-02-09 WO disclosed
CN-115667502-A Modified macrophages, compositions thereof and uses thereof 通用干细胞股份有限公司 2023-01-31 CN disclosed
WO-2022263807-A1 METHODS, COMPOSITIONS, AND KITS FOR PREPARING SEQUENCING LIBRARY GENEFIRST LIMITED (GB) 2022-12-22 WO disclosed
US-10550422-B2 Methods and compositions for labeling nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-02-04 US disclosed
EP-1937849-B1 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-05-29 EP disclosed
EP-1937850-B1 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-05-29 EP disclosed
US-7910335-B2 Methods and compositions for labeling nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-03-22 US disclosed
US-20110065907-A1 Methods and compositions for labeling nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-03-17 US disclosed
US-20100311063-A1 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2010-12-09 US disclosed
US-7767421-B2 Tagging nucleotide sequences with nucleoside analogue that comprises azide group reacted with substituted triarylphosphine; enhancing disease diagnosis and accuracy of toxicity bioassays PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-08-03 US disclosed
EP-1937850-A2 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS The President and Fellows of Harvard College (US) 2008-07-02 EP disclosed
EP-1937849-A2 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS The President and Fellows of Harvard College (US) 2008-07-02 EP disclosed
WO-2007120192-A2 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-10-25 WO disclosed
US-20070207476-A1 Methods and compositions for labeling nucleic acids NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-09-06 US disclosed
WO-2007050811-A2 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-05-03 WO disclosed
US-20070099222-A1 Tagging nucleotide sequences with nucleoside analogue that comprises azide group reacted with substituted triarylphosphine; enhancing disease diagnosis and accuracy of toxicity bioassays Life Technologies Corporation 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636304-B2 RNMT, RNGTT, NSUN2 P2RY2 2861/4885P2RY4 3525/4885P2RY6 2908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.